G5V (p.Gly5Val) variant of FOS (Protein c-Fos)
G5V (p.Gly5Val) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
G5V (p.Gly5Val) variant details
- p.Gly5Val
- gnomAD 14-75278996-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.341
- REVEL 0.15
- MetaLR 0.29
- MetaSVM -0.50
- CADD 27.00
- PolyPhen-2 0.69
- SIFT 0.10
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available