G5S (p.Gly5Ser) variant of FOS (Protein c-Fos)
G5S (p.Gly5Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
G5S (p.Gly5Ser) variant details
- p.Gly5Ser
- gnomAD rs1299824967
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.07
- MetaLR 0.17
- MetaSVM -0.94
- CADD 23.70
- PolyPhen-2 0.57
- SIFT 0.38
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available