G41S (p.Gly41Ser) variant of FOS (Protein c-Fos)
G41S (p.Gly41Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
G41S (p.Gly41Ser) variant details
- p.Gly41Ser
- gnomAD 14-75279103-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.484
- REVEL 0.30
- MetaLR 0.46
- MetaSVM -0.26
- CADD 25.50
- PolyPhen-2 1.00
- SIFT 0.22
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available