G41C (p.Gly41Cys) variant of FOS (Protein c-Fos)
G41C (p.Gly41Cys) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
G41C (p.Gly41Cys) variant details
- p.Gly41Cys
- ExAC rs780840095
- gnomAD rs780840095
- Missense
- Variant Prioritization Score for Impact Estimate 0.606
- REVEL 0.51
- MetaLR 0.48
- MetaSVM -0.06
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available