F60L (p.Phe60Leu) variant of FOS (Protein c-Fos)
F60L (p.Phe60Leu) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data, published literature, and structural context.
F60L (p.Phe60Leu) variant details
- p.Phe60Leu
- gnomAD 14-75279915-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.36
- REVEL 0.37
- MetaLR 0.33
- MetaSVM -0.48
- CADD 23.60
- PolyPhen-2 0.97
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available