D52E (p.Asp52Glu) variant of FOS (Protein c-Fos)
D52E (p.Asp52Glu) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
D52E (p.Asp52Glu) variant details
- p.Asp52Glu
- gnomAD rs1897206461
- Missense
- Variant Prioritization Score for Impact Estimate 0.157
- REVEL 0.07
- MetaLR 0.12
- MetaSVM -1.01
- CADD 18.90
- SIFT 0.20
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available