D25G (p.Asp25Gly) variant of FOS (Protein c-Fos)
D25G (p.Asp25Gly) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
D25G (p.Asp25Gly) variant details
- p.Asp25Gly
- gnomAD 14-75279056-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.444
- REVEL 0.29
- MetaLR 0.44
- MetaSVM -0.07
- CADD 32.00
- PolyPhen-2 0.98
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available