C50R (p.Cys50Arg) variant of FOS (Protein c-Fos)
C50R (p.Cys50Arg) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
C50R (p.Cys50Arg) variant details
- p.Cys50Arg
- gnomAD rs1386493581
- Missense
- Variant Prioritization Score for Impact Estimate 0.362
- REVEL 0.22
- MetaLR 0.11
- MetaSVM -1.06
- CADD 23.40
- PolyPhen-2 0.42
- SIFT 0.60
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available