A8S (p.Ala8Ser) variant of FOS (Protein c-Fos)
A8S (p.Ala8Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
A8S (p.Ala8Ser) variant details
- p.Ala8Ser
- gnomAD 14-75279004-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.03
- MetaLR 0.13
- MetaSVM -0.95
- CADD 21.70
- PolyPhen-2 0.01
- SIFT 0.56
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available