A8E (p.Ala8Glu) variant of FOS (Protein c-Fos)
A8E (p.Ala8Glu) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
A8E (p.Ala8Glu) variant details
- p.Ala8Glu
- gnomAD rs1283649601
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.16
- MetaLR 0.23
- MetaSVM -0.62
- CADD 24.10
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available