A80S (p.Ala80Ser) variant of FOS (Protein c-Fos)
A80S (p.Ala80Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
A80S (p.Ala80Ser) variant details
- p.Ala80Ser
- 1000Genomes rs200973067
- ExAC rs200973067
- TOPMed rs200973067
- gnomAD rs200973067
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.05
- MetaLR 0.08
- MetaSVM -1.10
- CADD 19.80
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the 1KG:ASW population (allele frequency 0.0098)
- Structural context available