A54D (p.Ala54Asp) variant of FOS (Protein c-Fos)
A54D (p.Ala54Asp) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
A54D (p.Ala54Asp) variant details
- p.Ala54Asp
- gnomAD 14-75279896-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.06
- MetaLR 0.11
- MetaSVM -1.04
- CADD 22.40
- PolyPhen-2 0.02
- SIFT 0.48
- Population evidence available
- Structural context available
- Literature evidence available