A46V (p.Ala46Val) variant of FOS (Protein c-Fos)
A46V (p.Ala46Val) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
A46V (p.Ala46Val) variant details
- p.Ala46Val
- gnomAD rs1203741003
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.04
- MetaLR 0.08
- MetaSVM -1.07
- CADD 20.80
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 8.1e-06)
- Structural context available