A46T (p.Ala46Thr) variant of FOS (Protein c-Fos)
A46T (p.Ala46Thr) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
A46T (p.Ala46Thr) variant details
- p.Ala46Thr
- gnomAD 14-75279118-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.258
- REVEL 0.07
- MetaLR 0.04
- MetaSVM -1.03
- CADD 21.00
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available