A46S (p.Ala46Ser) variant of FOS (Protein c-Fos)
A46S (p.Ala46Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
A46S (p.Ala46Ser) variant details
- p.Ala46Ser
- gnomAD 14-75279118-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.26
- REVEL 0.10
- MetaLR 0.03
- MetaSVM -1.00
- CADD 15.70
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available