A46G (p.Ala46Gly) variant of FOS (Protein c-Fos)
A46G (p.Ala46Gly) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
A46G (p.Ala46Gly) variant details
- p.Ala46Gly
- gnomAD 14-75279119-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- REVEL 0.05
- MetaLR 0.08
- MetaSVM -1.07
- CADD 17.60
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available