A20T (p.Ala20Thr) variant of FOS (Protein c-Fos)
A20T (p.Ala20Thr) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
A20T (p.Ala20Thr) variant details
- p.Ala20Thr
- ESP rs139508491
- ExAC rs139508491
- TOPMed rs139508491
- gnomAD rs139508491
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.27
- MetaLR 0.44
- MetaSVM -0.16
- CADD 26.50
- PolyPhen-2 0.98
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available