A20S (p.Ala20Ser) variant of FOS (Protein c-Fos)
A20S (p.Ala20Ser) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data, published literature, and structural context.
A20S (p.Ala20Ser) variant details
- p.Ala20Ser
- gnomAD 14-75279040-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.405
- REVEL 0.21
- MetaLR 0.37
- MetaSVM -0.50
- CADD 28.70
- PolyPhen-2 0.99
- SIFT 0.15
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available