A20P (p.Ala20Pro) variant of FOS (Protein c-Fos)
A20P (p.Ala20Pro) in FOS (Protein c-Fos) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
A20P (p.Ala20Pro) variant details
- p.Ala20Pro
- ESP rs139508491
- ExAC rs139508491
- TOPMed rs139508491
- gnomAD rs139508491
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.24
- MetaLR 0.41
- MetaSVM -0.38
- CADD 26.80
- PolyPhen-2 1.00
- SIFT 0.08
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available