V85I (p.Val85Ile) variant of FLT3 (P36888)
V85I (p.Val85Ile) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
V85I (p.Val85Ile) variant details
- p.Val85Ile
- TOPMed rs1876608151
- gnomAD rs1876608151
- Missense
- Variant Prioritization Score for Impact Estimate 0.0662
- REVEL 0.02
- MetaLR 0.05
- MetaSVM -1.03
- CADD 0.26
- PolyPhen-2 0.00
- SIFT 0.23
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available