V75M (p.Val75Met) variant of FLT3 (P36888)
V75M (p.Val75Met) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V75M (p.Val75Met) variant details
- p.Val75Met
- ExAC rs773277609
- gnomAD rs773277609
- Missense
- Variant Prioritization Score for Impact Estimate 0.408
- REVEL 0.23
- MetaLR 0.33
- MetaSVM -0.70
- CADD 14.70
- PolyPhen-2 0.28
- SIFT 0.02
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available