V56L (p.Val56Leu) variant of FLT3 (P36888)
V56L (p.Val56Leu) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
V56L (p.Val56Leu) variant details
- p.Val56Leu
- gnomAD rs1193293388
- Missense
- Variant Prioritization Score for Impact Estimate 0.221
- REVEL 0.08
- MetaLR 0.27
- MetaSVM -0.80
- CADD 19.00
- PolyPhen-2 0.02
- SIFT 0.24
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available