V32L (p.Val32Leu) variant of FLT3 (P36888)
V32L (p.Val32Leu) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
V32L (p.Val32Leu) variant details
- p.Val32Leu
- TOPMed rs1877417496
- Missense
- Variant Prioritization Score for Impact Estimate 0.325
- REVEL 0.07
- MetaLR 0.20
- MetaSVM -0.97
- CADD 19.20
- PolyPhen-2 0.00
- SIFT 0.29
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available