V16A (p.Val16Ala) variant of FLT3 (P36888)
V16A (p.Val16Ala) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
V16A (p.Val16Ala) variant details
- p.Val16Ala
- TOPMed rs1877421197
- Missense
- Variant Prioritization Score for Impact Estimate 0.413
- REVEL 0.33
- MetaLR 0.52
- MetaSVM -0.16
- CADD 22.60
- PolyPhen-2 0.98
- SIFT 0.26
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available