V15L (p.Val15Leu) variant of FLT3 (P36888)
V15L (p.Val15Leu) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
V15L (p.Val15Leu) variant details
- p.Val15Leu
- gnomAD rs1184783541
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.11
- MetaLR 0.23
- MetaSVM -0.90
- CADD 24.00
- PolyPhen-2 0.00
- SIFT 0.53
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available