V15A (p.Val15Ala) variant of FLT3 (P36888)
V15A (p.Val15Ala) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
V15A (p.Val15Ala) variant details
- p.Val15Ala
- ESP rs376016497
- ExAC rs376016497
- TOPMed rs376016497
- gnomAD rs376016497
- Missense
- Variant Prioritization Score for Impact Estimate 0.227
- REVEL 0.17
- MetaLR 0.27
- MetaSVM -0.78
- CADD 17.10
- PolyPhen-2 0.00
- SIFT 0.51
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available