T90I (p.Thr90Ile) variant of FLT3 (P36888)
T90I (p.Thr90Ile) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
T90I (p.Thr90Ile) variant details
- p.Thr90Ile
- ExAC rs760407576
- gnomAD rs760407576
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.17
- MetaLR 0.08
- MetaSVM -0.97
- CADD 18.10
- PolyPhen-2 0.26
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available