T26I (p.Thr26Ile) variant of FLT3 (P36888)
T26I (p.Thr26Ile) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
T26I (p.Thr26Ile) variant details
- p.Thr26Ile
- ExAC rs754142696
- gnomAD rs754142696
- Missense
- Variant Prioritization Score for Impact Estimate 0.376
- REVEL 0.34
- MetaLR 0.27
- MetaSVM -0.71
- CADD 20.40
- PolyPhen-2 0.07
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available