S86P (p.Ser86Pro) variant of FLT3 (P36888)
S86P (p.Ser86Pro) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
S86P (p.Ser86Pro) variant details
- p.Ser86Pro
- ExAC rs758850662
- TOPMed rs758850662
- gnomAD rs758850662
- Missense
- Variant Prioritization Score for Impact Estimate 0.183
- REVEL 0.09
- MetaLR 0.05
- MetaSVM -1.07
- CADD 7.55
- PolyPhen-2 0.04
- SIFT 0.27
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available