S86F (p.Ser86Phe) variant of FLT3 (P36888)
S86F (p.Ser86Phe) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
S86F (p.Ser86Phe) variant details
- p.Ser86Phe
- gnomAD rs1232322315
- Missense
- Variant Prioritization Score for Impact Estimate 0.155
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.06
- CADD 7.09
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available