S111F (p.Ser111Phe) variant of FLT3 (P36888)
S111F (p.Ser111Phe) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
S111F (p.Ser111Phe) variant details
- p.Ser111Phe
- ESP rs144209806
- ExAC rs144209806
- TOPMed rs144209806
- gnomAD rs144209806
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.05
- MetaLR 0.07
- MetaSVM -1.01
- CADD 15.50
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the African/African-American population (allele frequency 0.00056)
- Structural context available