S102F (p.Ser102Phe) variant of FLT3 (P36888)
S102F (p.Ser102Phe) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
S102F (p.Ser102Phe) variant details
- p.Ser102Phe
- TOPMed rs774223271
- gnomAD rs774223271
- Missense
- Variant Prioritization Score for Impact Estimate 0.399
- REVEL 0.22
- MetaLR 0.10
- MetaSVM -1.05
- CADD 23.60
- PolyPhen-2 0.01
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available