P69R (p.Pro69Arg) variant of FLT3 (P36888)
P69R (p.Pro69Arg) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P69R (p.Pro69Arg) variant details
- p.Pro69Arg
- ExAC rs752457971
- gnomAD rs752457971
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.08
- MetaLR 0.19
- MetaSVM -0.99
- CADD 7.14
- PolyPhen-2 0.00
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 3.7e-05)
- Structural context available