P69H (p.Pro69His) variant of FLT3 (P36888)
P69H (p.Pro69His) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
P69H (p.Pro69His) variant details
- p.Pro69His
- ExAC rs752457971
- gnomAD rs752457971
- Missense
- Variant Prioritization Score for Impact Estimate 0.191
- REVEL 0.05
- MetaLR 0.21
- MetaSVM -0.93
- CADD 11.50
- PolyPhen-2 0.00
- SIFT 0.40
- Most common in the South Asian population (allele frequency 3.5e-05)
- Structural context available