P60L (p.Pro60Leu) variant of FLT3 (P36888)
P60L (p.Pro60Leu) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
P60L (p.Pro60Leu) variant details
- p.Pro60Leu
- ExAC rs777905087
- TOPMed rs777905087
- gnomAD rs777905087
- Missense
- Variant Prioritization Score for Impact Estimate 0.12
- REVEL 0.09
- MetaLR 0.15
- MetaSVM -0.96
- CADD 2.65
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available