P54S (p.Pro54Ser) variant of FLT3 (P36888)
P54S (p.Pro54Ser) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P54S (p.Pro54Ser) variant details
- p.Pro54Ser
- TOPMed rs914265393
- Missense
- Variant Prioritization Score for Impact Estimate 0.164
- REVEL 0.06
- MetaLR 0.16
- MetaSVM -0.97
- CADD 14.60
- PolyPhen-2 0.00
- SIFT 0.81
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available