P54L (p.Pro54Leu) variant of FLT3 (P36888)
P54L (p.Pro54Leu) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
P54L (p.Pro54Leu) variant details
- p.Pro54Leu
- gnomAD rs1357370556
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.05
- MetaLR 0.23
- MetaSVM -0.89
- CADD 18.10
- PolyPhen-2 0.02
- SIFT 0.29
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available