P2S (p.Pro2Ser) variant of FLT3 (P36888)
P2S (p.Pro2Ser) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P2S (p.Pro2Ser) variant details
- p.Pro2Ser
- Ensembl rs2137844628
- Missense
- Variant Prioritization Score for Impact Estimate 0.331
- REVEL 0.10
- MetaLR 0.22
- MetaSVM -0.87
- CADD 22.30
- PolyPhen-2 0.03
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available