P2R (p.Pro2Arg) variant of FLT3 (P36888)
P2R (p.Pro2Arg) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P2R (p.Pro2Arg) variant details
- p.Pro2Arg
- TOPMed rs1879764124
- gnomAD rs1879764124
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.12
- MetaLR 0.13
- MetaSVM -0.95
- CADD 23.00
- PolyPhen-2 0.00
- SIFT 0.97
- Most common in the South Asian population (allele frequency 0.00041)
- Structural context available