P2Q (p.Pro2Gln) variant of FLT3 (P36888)
P2Q (p.Pro2Gln) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P2Q (p.Pro2Gln) variant details
- p.Pro2Gln
- TOPMed rs1879764124
- gnomAD rs1879764124
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.11
- MetaLR 0.19
- MetaSVM -0.91
- CADD 22.90
- PolyPhen-2 0.10
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 1.1e-06)
- Structural context available