P2L (p.Pro2Leu) variant of FLT3 (P36888)
P2L (p.Pro2Leu) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
P2L (p.Pro2Leu) variant details
- p.Pro2Leu
- TOPMed rs1879764124
- gnomAD rs1879764124
- Missense
- Variant Prioritization Score for Impact Estimate 0.326
- REVEL 0.12
- MetaLR 0.18
- MetaSVM -0.92
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.19
- Population evidence available
- Structural context available