P12S (p.Pro12Ser) variant of FLT3 (P36888)
P12S (p.Pro12Ser) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
P12S (p.Pro12Ser) variant details
- p.Pro12Ser
- TOPMed rs1879760287
- Missense
- Variant Prioritization Score for Impact Estimate 0.319
- REVEL 0.15
- MetaLR 0.20
- MetaSVM -0.98
- CADD 21.00
- PolyPhen-2 0.00
- SIFT 0.57
- Population evidence available
- Structural context available