N43S (p.Asn43Ser) variant of FLT3 (P36888)
N43S (p.Asn43Ser) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
N43S (p.Asn43Ser) variant details
- p.Asn43Ser
- TOPMed rs979689401
- gnomAD rs979689401
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.14
- MetaLR 0.22
- MetaSVM -0.86
- CADD 19.70
- PolyPhen-2 0.01
- SIFT 0.48
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available