N42K (p.Asn42Lys) variant of FLT3 (P36888)
N42K (p.Asn42Lys) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
N42K (p.Asn42Lys) variant details
- p.Asn42Lys
- ExAC rs745739442
- TOPMed rs745739442
- gnomAD rs745739442
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.15
- MetaLR 0.29
- MetaSVM -0.53
- CADD 16.70
- PolyPhen-2 0.01
- SIFT 0.44
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available