N39Y (p.Asn39Tyr) variant of FLT3 (P36888)
N39Y (p.Asn39Tyr) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
N39Y (p.Asn39Tyr) variant details
- p.Asn39Tyr
- ExAC rs748910439
- gnomAD rs748910439
- Missense
- Variant Prioritization Score for Impact Estimate 0.222
- REVEL 0.16
- MetaLR 0.24
- MetaSVM -0.83
- CADD 15.70
- PolyPhen-2 0.02
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available