M20V (p.Met20Val) variant of FLT3 (P36888)
M20V (p.Met20Val) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
M20V (p.Met20Val) variant details
- p.Met20Val
- ExAC rs765418650
- TOPMed rs765418650
- gnomAD rs765418650
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.09
- MetaLR 0.20
- MetaSVM -0.97
- CADD 2.07
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the South Asian population (allele frequency 0.00043)
- Structural context available