L11P (p.Leu11Pro) variant of FLT3 (P36888)
L11P (p.Leu11Pro) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
L11P (p.Leu11Pro) variant details
- p.Leu11Pro
- Ensembl rs1011781461
- Missense
- Variant Prioritization Score for Impact Estimate 0.505
- REVEL 0.54
- MetaLR 0.35
- MetaSVM -0.52
- CADD 27.60
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 2.4e-05)
- Structural context available