L104F (p.Leu104Phe) variant of FLT3 (P36888)
L104F (p.Leu104Phe) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
L104F (p.Leu104Phe) variant details
- p.Leu104Phe
- ExAC rs781258193
- gnomAD rs781258193
- Missense
- Variant Prioritization Score for Impact Estimate 0.322
- REVEL 0.14
- MetaLR 0.07
- MetaSVM -1.09
- CADD 18.00
- PolyPhen-2 0.00
- SIFT 0.69
- Most common in the HGDP:PATHAN population (allele frequency 0.021)
- Structural context available