K108N (p.Lys108Asn) variant of FLT3 (P36888)
K108N (p.Lys108Asn) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
K108N (p.Lys108Asn) variant details
- p.Lys108Asn
- gnomAD rs1227729363
- Missense
- Variant Prioritization Score for Impact Estimate 0.143
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.04
- CADD 19.20
- PolyPhen-2 0.20
- SIFT 0.12
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available