I38V (p.Ile38Val) variant of FLT3 (P36888)
I38V (p.Ile38Val) in FLT3 (P36888) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
I38V (p.Ile38Val) variant details
- p.Ile38Val
- ExAC rs762242697
- TOPMed rs762242697
- gnomAD rs762242697
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.24
- MetaLR 0.28
- MetaSVM -0.57
- CADD 20.80
- PolyPhen-2 0.13
- SIFT 0.13
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available